Image highlight: Rare osseous metaplasia

Histopathological polyp specimen demonstrating adenomatous surface epithelium and osseous metaplasia with surface osteoclasts

This week’s image is taken from a recently published case report by Dr Victoria White of the Department of Colorectal Surgery, Derby City General Hospital, Derby.


Journal of Medical Case Reports 2008, 2:130

A 63-year-old woman, who drank 2 to 3 litres of gin per week, presented with a history of melaena. Colonoscopy revealed her to have a pedunculated ulcerating polyp. Histological examination demonstrated multiple areas of osseous metaplasia within the polyp stroma. Heterotopic ossification in colonic adenomas is a particularly rare phenomenon, with the majority of cases occurring within malignant lesions. The suggested mechanisms for its aetiology still remain unclear. [View full case report and more images]


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