Posts Tagged ‘evidence-based medicine’

Case report of the week: bloody tears

September 21, 2009

The shocking case of a child who cries tears of blood every day was featured in newspapers a few weeks ago. The mother of the patient complained that “Every doctor tells us they’ve never seen anything like this before in all their many years of being a doctor”.

Last week, Cases Journal published a case report detailing the condition of a young girl who suffered subconjunctival hemorrhage, also leading to bloody tears.

An important lesson could be learnt from the publication of this case report. This gives us a poignant reminder of the central role that case reports can play in informing the medical community.

Read the case report in full here.

Bloody tears and hematohidrosis in a patient of PF3 dysfunction: a case report” – Kusum L Mishra

by Lindsay Dytham – Editorial Assistant


Videos from “Celebrating case reports, the stories in healthcare”

July 1, 2009

If you missed out on Cases Network’s meeting “Celebrating case reports, the stories in health care” at the Royal College of Physicians last month, you can catch up on our speakers’ talks as the videos are now online.

It was a fascinating conference, and we were delighted to have such great speakers taking part and sharing their views and experiences of medical case reports.

The sessions sparked lively debate on the day, and we hope you will continue the discussion in the comments below.

Thanks again to all our speakers and delegates for making it such an interesting and memorable day!

Elizabeth Slade, Publisher

Christian Koch on publishing case reports and TV’s Dr House

May 1, 2009

We caught up with Professor Christian Koch, one of our Deputy Editors for Journal of Medical Case Reports, for a few insights on his work with the journal.

What would you say is the ‘best’ paper you have reviewed and why?

CK: I have handled many “good” papers, each unique in its own way. However, one of the very best ones I can remember was one that dealt with the question whether several tumors in an individual could represent a syndrome, although only a subset of “potential” candidate genes had been tested and was negative (J Med Case Reports. 2007 Mar 28;1:9).

This should remind us of the initial observations and publications of the combination of medullary thyroid cancer and pheochromocytoma in some patients (for instance, Sipple syndrome or Multiple endocrine neoplasia type 2) many decades ago and the discovery of the RET proto-oncogene in 1985 and finally the implication of its role in MEN2 in 1993.

All this underscores that careful observation, a sharp mind, and sometimes an approach similar to the one of “Dr. House” (on TV) will not only help our individual patients but many others in the future.

Why do you feel it is important to publish case reports?

CK: We are in an era of “evidence-based medicine”. However, we finally begin to realize that much of the so-called evidence is derived from heterogeneous patient populations and not necessarily applicable to our individual patients we see on a daily basis. Numerous recent studies including ENHANCE, ACCORD, ADVANCE, and the VA Diabetes Outcome Trial, have shown us that heterogeneity of patients, equipment, investigators, etc. can limit our thrive for evidence on a large scale and make us think about personalized, individualized medicine…. that is, why publishing case reports is important in my mind.

Celebrating case reports at the Royal College of Physicians

April 9, 2009

We’re pleased to invite you to a special academic meeting that Cases Network is hosting – “Celebrating case reports, the stories in health care“.

The meeting will take place at the Royal College of Physicians here in London, on Friday 15th May. We have a fantastic line-up of speakers, to cover topics such as the role of case reports in evidence-based medicine, in primary care, and their importance in the developing world. We will also cover the history of case reports as well as looking to the future with medicine 2.0 and the role of patients in health care.

Places are still available, so register now.

The registration fee (£75) allows each delegate to publish a case report for free in Cases Journal (normally £199).

We look forward to meeting you!